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Kawasaki disease: Part II. Complications and treatment
Kawasaki disease, or mucocutaneous lymph node syndrome, is the leading cause of acquired heart disease in children in the United States and other developed countries. Coronary artery lesions are the most significant cause of morbidity and mortality. Treatment should ideally be provided within 10 days of symptom onset to reduce the risk of coronary artery complications. The standard of care for treatment is intravenous immunoglobulin plus aspirin, but adding corticosteroids may provide additional benefit for high-risk patients. Some patients do not respond to intravenous immunoglobulin and require additional therapy. Part I...
Source: Journal of the American Academy of Dermatology - September 20, 2013 Category: Dermatology Authors: Stephanie Bayers, Stanford T. Shulman, Amy S. Paller Tags: Continuing Medical Education Source Type: research

Prevention and management of glucocorticoid-induced side effects: A comprehensive review
Part 2 of this 4-part continuing medical education series continues with a discussion of the prevention and  management of gastrointestinal side effects associated with corticosteroid use, including peptic ulcer disease, gastrointestinal bleeding, and pancreatitis, followed by a review of corticosteroid-related endocrinologic side effects, such as diabetes, adrenal suppression, and Cushing syndrome.
Source: Journal of the American Academy of Dermatology - December 14, 2016 Category: Dermatology Authors: Avrom Caplan, Nicole Fett, Misha Rosenbach, Victoria P. Werth, Robert G. Micheletti Tags: Continuing medical education Source Type: research

Effectiveness of Kinesiotaping and Subacromial Corticosteroid Injection in Shoulder Impingement Syndrome
Objective: The aim of this study was to investigate whether kinesiotaping or subacromial corticosteroid injection provides additional benefit when used with nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with shoulder impingement syndrome. Design: Patients with shoulder impingement syndrome were divided into 3 groups as follows: NSAID group (n = 33), kinesiotaping group (kinesiotaping + NSAID) (n = 33), and injection group (subacromial corticosteroid injection + NSAID) (n = 33). Outcome measures including visual analog scale, shoulder ranges of motion, Shoulder Disability Questionnaire, and University of Califo...
Source: American Journal of Physical Medicine and Rehabilitation - July 19, 2016 Category: Rehabilitation Tags: Original Research Articles: CME Article . 2016 Series . Number 8 Source Type: research

Autologous Blood-Derived Products Compared With Corticosteroids for Treatment of Plantar Fasciopathy: A Systematic Review and Meta-Analysis
Conclusions The results of this meta-analysis suggest that platelet-rich plasma may provide a long-term effect in relieving pain in plantar fasciopathy patients. To Claim CME Credits Complete the self-assessment activity and evaluation online at http://www.physiatry.org/JournalCME CME Objectives Upon completion of this article, the reader should be able to: (1) Compare the efficacy of whole blood (WB), platelet-rich plasma (PRP), and corticosteroid (CS) in short-term pain reduction in patients with plantar fasciopathy (PF); (2) Compare the efficacy of WB, PRP, and CS in long-term pain reduction in patients with PF;...
Source: American Journal of Physical Medicine and Rehabilitation - April 18, 2019 Category: Rehabilitation Tags: Original Research Articles: CME Article . 2019 Series . Number 5 Source Type: research

Retrospective Analysis of Fractures and Factors Causing Ambulation Loss After Lower Limb Fractures in Duchenne Muscular Dystrophy
Conclusions Fracture represents a significant risk in patients with Duchenne muscular dystrophy; both slower walking speed and ankle contracture confer an increased risk of ambulation loss after fracture. To Claim CME Credits Complete the self-assessment activity and evaluation online at http://www.physiatry.org/JournalCME CME Objectives Upon completion of this article, the reader should be able to: (1) Identify the main factors that are associated with ambulation loss after fracture in patients with Duchenne muscular dystrophy; (2) Identify the risk of fracture in the Duchenne muscular dystrophy population; and (3...
Source: American Journal of Physical Medicine and Rehabilitation - August 22, 2020 Category: Rehabilitation Tags: CME Article . 2020 Series . Number 9 Source Type: research

Evaluating Hematologist's Knowledge of CAR T-Cell Therapy in Hematologic Malignancies
Conclusions: This activity found knowledge and competence deficits for hem/onc practitioners related to using CAR T-cell therapy for the treatment of patients with hematologic malignancies. Additionally, the activity demonstrated large gaps in confidence discussing CAR T-cell therapy with patients/families and managing adverse events. There is sub-optimal awareness of CAR T-cell foundational knowledge, clinical trial data, and recognition of common therapy related adverse events and management strategies. Additional education is needed to improve the knowledge, competence, and confidence of academic and community hem/onc s...
Source: Blood - November 21, 2018 Category: Hematology Authors: Willis, L., Fagerlie, S. R., Neelapu, S. S. Tags: 902. Health Services Research-Malignant Diseases: Poster I Source Type: research

Are general practitioners well informed about fibromyalgia?
ConclusionIranian general practitioners are not well informed about FMS. Therefore, FMS should be specifically integrated in continuing medical education programs and undergraduate medical training curriculum.
Source: APLAR Journal of Rheumatology - July 22, 2015 Category: Rheumatology Authors: Nahid Kianmehr, Anousheh Haghighi, Ali Bidari, Yaser Sharafian Ardekani, Mohammad Ali Karimi Tags: Original Article Source Type: research

A Micro-Learning Approach Improves Knowledge among Allergists and Otolaryngologists related to Chronic Rhinosinusitis with Nasal Polyps
This study examined whether online continuing medical education (CME) could improve the knowledge and competence of allergists and otolaryngologists in the management of CRSwNPs.
Source: Journal of Allergy and Clinical Immunology - February 1, 2022 Category: Allergy & Immunology Authors: Sara Thorpe, Karen Badal, Piyali Chatterjee-Shin Source Type: research

DRESS syndrome: Part II. Management and therapeutics
The appropriate management of the drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is paramount because it is associated with significant morbidity and mortality. This syndrome shares clinical features with other dermatologic conditions, including other severe cutaneous drug reactions, requiring the clinician to carefully examine the proposed criteria to make the appropriate diagnosis. Once the diagnosis of DRESS syndrome has been established, the next step in management is immediate cessation of the causative medication(s). In cases in which the culprit drug is not obvious, clinicians must use their ...
Source: Journal of the American Academy of Dermatology - April 22, 2013 Category: Dermatology Authors: Zain Husain, Bobby Y. Reddy, Robert A. Schwartz Tags: Continuing Medical Education Source Type: research

Systemic mastocytosis in adults: 2013 update on diagnosis, risk stratification, and management
Disease overview:Systemic mastocytosis (SM) results from a clonal proliferation of abnormal mast cells (MC) in one or more extracutaneous organs. Diagnosis:The major criterion is presence of multifocal clusters of morphologically abnormal MC in the bone marrow. Minor diagnostic criteria include elevated serum tryptase level, abnormal MC expression of CD25 and/or CD2, and presence of KITD816V. Risk stratification:The 2008 World Health Organization (WHO) classification of SM has been shown to be prognostically relevant. Classification of SM patients into indolent (SM), aggressive SM (ASM), SM associated with a clonal non‐M...
Source: American Journal of Hematology - May 30, 2013 Category: Hematology Authors: Animesh Pardanani Tags: A Continuing Medical Education Series Source Type: research

Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome) Part II. Prognosis, management, and future directions
Both mycosis fungoides (MF) and Sézary syndrome (SS) have a chronic, relapsing course, with patients frequently undergoing multiple, consecutive therapies. Treatment is aimed at the clearance of skin disease, the minimization of recurrence, the prevention of disease progression, and the preservation of quality of life. Other important considerations are symptom severity, including pruritus and patient age/comorbidities. In general, for limited patch and plaque disease, patients have excellent prognosis on ≥1 topical formulations, including topical corticosteroids and nitrogen mustard, with widespread patch/plaque diseas...
Source: Journal of the American Academy of Dermatology - January 16, 2014 Category: Dermatology Authors: Sarah I. Jawed, Patricia L. Myskowski, Steven Horwitz, Alison Moskowitz, Christiane Querfeld Tags: Continuing Medical Education Source Type: research

POEMS syndrome: Update on diagnosis, risk‐stratification, and management
Disease overview: POEMS syndrome is a paraneoplastic syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyradiculoneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease. Minor features include organomegaly, endocrinopathy, characteristic skin changes, papilledema, extravascular volume overload, and thrombocytosis. Diagnoses are often delayed because the syndrome is rare and can be mistaken for other neurologic disorders, most commonly chronic inflammatory demyelinating polyradiculone...
Source: American Journal of Hematology - September 1, 2015 Category: Hematology Authors: Angela Dispenzieri Tags: Annual Clinical Updates in Hematological Malignancies: A Continuing Medical Education Series Source Type: research

POEMS syndrome: 2017 Update on diagnosis, risk stratification, and management
Abstract Disease OverviewPOEMS syndrome is a paraneoplastic syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyradiculoneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease. Minor features include organomegaly, endocrinopathy, characteristic skin changes, papilledema, extravascular volume overload, and thrombocytosis. Diagnoses are often delayed because the syndrome is rare and can be mistaken for other neurologic disorders, most commonly chronic inflammatory demyelinating polyrad...
Source: American Journal of Hematology - July 12, 2017 Category: Hematology Authors: Angela Dispenzieri Tags: ANNUAL CLINICAL UPDATES IN HEMATOLOGICAL MALIGNANCIES: A CONTINUING MEDICAL EDUCATION SERIES Source Type: research

CME Exam 1: Corticosteroids, But Not TNF Antagonists, Are Associated with Adverse COVID-19 Outcomes in Patients With Inflammatory Bowel Diseases: Results from an International Registry
Source: Gastroenterology - July 31, 2020 Category: Gastroenterology Tags: Continuing Medical Education (CME)/MOC Activity Source Type: research